The Leukodystrophies

CNS myelin - oligodendrocyte - MBP, PLP
PNS myelin - schwann - P0, MBP, P2

Central myelination begins in 5th fetal month.

White matter tracts

Alexander disease

X-linked adrenoleukodystrophy

Globoid cell leukoystrophies (Krabbe disease)

Metachromatic leukodystrophy

missed a stretch

Canavan disease

Cerebrotendinous xanthomatosis

Pelizaeus-Merzbacher Disease

Spastic Paraplegia (SPG2)

Cockayne syndrome